| Product Name |
Spermine Tetrahydrochloride (SPT) |
|---|---|
| CAS No. | 306-67-2 |
| MF | C10H30Cl4N4 |
| MW | 348.19 g/mol |
| Specification | ≥98% (HPLC) |
| Appearance | White crystalline powder |
| Packing | 1kg/bag; 25kg/drum (customized available) |
| Applications |
Research in aging, neuroprotection, DNA stabilization, biochemistry |
Spermine Tetrahydrochloride is a stable crystalline salt form of spermine, a naturally occurring polyamine present in all eukaryotic cells. It is widely applied in molecular biology, cellular aging research, and neurobiology studies.
As a polyamine, SPT plays a crucial role in DNA stabilization, oxidative stress reduction, and cellular longevity. Due to its improved stability and solubility compared to free spermine, the tetrahydrochloride form is preferred for laboratory research and pharmaceutical development.
🧬 DNA Stabilization – Enhances chromatin structure stability
⚡ Anti-oxidant Function – Protects cells from oxidative stress
🧠 Neuroprotection – Investigated in Alzheimer’s and Parkinson’s research
🔬 Biological Research Utility – Ideal for in vitro and in vivo studies
🛡️ Stable Salt Form – More reliable storage and solubility than base spermine
HPLC purity ≥98%
GMP-compliant production
Bulk supply available for laboratories and research institutes
OEM/ODM packaging services
Tested for heavy metals and microbial safety
| Specification | Qualified Testing Result | Actual Testing Result | Test Method |
|---|---|---|---|
| Part 1. Physical & Chemical Analysis | |||
| Appearance | White crystalline powder | Complied | Visual |
| Assay (HPLC) | ≥98.0% | 98.9% | HPLC |
| Solubility | Freely soluble in water | Complied | USP |
| Melting Point | ≥290 °C (dec.) | 292 °C | USP |
| Loss on Drying | ≤0.5% | 0.22% | USP <731> |
| Residue on Ignition | ≤0.1% | 0.05% | USP <281> |
| Part 2. Heavy Metal Analysis & Control | |||
| Total Heavy Metals | ≤10 ppm | Complied | AAS |
| Lead (Pb) | ≤3 ppm | <1 ppm | ICP-MS |
| Arsenic (As) | ≤1 ppm | <0.1 ppm | ICP-MS |
| Cadmium (Cd) | ≤1 ppm | <0.05 ppm | ICP-MS |
| Mercury (Hg) | ≤0.1 ppm | <0.01 ppm | ICP-MS |
| Part 3. Microbiological Analysis & Control | |||
| Total Plate Count (cfu/g) | ≤1,000 | <100 | USP <61> |
| Yeast & Mold (cfu/g) | ≤100 | <10 | USP <61> |
| E. coli | Negative | Negative | USP <62> |
| Salmonella (per 25 g) | Negative | Negative | USP <62> |
Gerontology: Research on cellular senescence & anti-aging
Neurology: Protective effects on neurons in degenerative models
Genetics: Used in studies of DNA/RNA stabilization
Pharmaceutical R&D: Precursor or excipient in drug formulations
1kg/aluminium foil bag, with two plastic bags inside.
Gross Weight: 1.5kg Size: 18cmxH27cm
25kg/fiber drum, with two plastic bags inside.
Gross Weight: 28kg Size: 42cmxH52cm Volume: 0.0625mg/Drum.
DHL / FEDEX / EMS / E-PACKET / BY AIR / BY SEA
1. ≤50kg, Express delivery(DHL /FEDEX) recommended, usually called as DDU service;
2. ≤500kg, Air shipping recommended, usually called as CIF service;
3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;
4. For high value products, please select air shipping and express delivery for safe.
We will contact you within 1 working day, please pay attention to the email with the suffix “forrest@oriherb.com”.
