| Product Name |
Levomefolate calcium |
|---|---|
| CAS No. | 151533-22-1 |
| MF | C20H23CaN7O6 |
| MW | 497.52 |
| Purity | ≥98.0% |
| Appearance | White to light yellow powder |
| Packing | 1kg/bag,25kg/drum |
| Apply |
Methylated folate supplement, homocysteine regulation, prenatal nutrition, cognitive support |
Levomefolate Calcium, also known as L-5-Methyltetrahydrofolate calcium salt, is the biologically active form of folate and the most efficient form for the human body to utilize. Unlike synthetic folic acid, it does not require enzymatic conversion via MTHFR before entering the folate cycle, making it especially beneficial for individuals with MTHFR gene mutations.
Key benefits include:
Direct bioavailability – readily absorbed and utilized without metabolic conversion
Supports prenatal health – critical for fetal neural tube development
Regulates homocysteine – promotes cardiovascular health
Neuroprotective effects – supports mood, memory, and cognitive function
High purity ≥98.0% verified by HPLC
Non-GMO, allergen-free, solvent-free manufacturing process
Produced under GMP, ISO, HACCP certifications
Excellent stability and solubility in formulation processes
Consistent batch quality for nutraceutical and pharmaceutical applications
| Specification | Qualified Testing Result | Actual Testing Result | Test Method |
|---|---|---|---|
| Part 1. Physical & Chemical Analysis | |||
| Appearance | White to light yellow powder | Complied | Visual |
| Odor | Characteristic | Complied | Organoleptic |
| Assay (HPLC) | ≥98.0% | 98.6% | HPLC |
| Loss on Drying | ≤5.0% | 1.21% | USP <731> |
| Residue on Ignition | ≤0.5% | 0.08% | USP <281> |
| Solubility | Soluble in water | Complied | Visual |
| Part 2. Heavy Metal Analysis & Chemical Control | |||
| Total Heavy Metals | ≤10 ppm | Complied | AAS |
| Lead (Pb) | ≤3 ppm | <0.5 ppm | ICP-MS |
| Arsenic (As) | ≤1 ppm | <0.1 ppm | ICP-MS |
| Cadmium (Cd) | ≤1 ppm | <0.05 ppm | ICP-MS |
| Mercury (Hg) | ≤0.1 ppm | <0.01 ppm | ICP-MS |
| Part 3. Microbiological Analysis & Control | |||
| Total Plate Count (cfu/g) | ≤1,000 | <100 | USP <61> |
| Yeast & Mold (cfu/g) | ≤100 | <10 | USP <61> |
| E. coli | Negative | Negative | USP <62> |
| Salmonella (per 25 g) | Negative | Negative | USP <62> |
Nutraceuticals – brain health, mood support, cardiovascular supplements
Prenatal nutrition – folate supplementation for pregnant women
Pharmaceuticals – homocysteine-lowering drugs, antidepressant adjuncts
Functional foods – fortified beverages and dietary products
Q: Is levomefolate calcium the same as methylfolate?
A: Yes, essentially. Levomefolate Calcium is the stabilized, salt form of the active compound L-Methylfolate. It is the identical, biologically active form of folate that your body can use directly, unlike synthetic folic acid which requires conversion.
Q: What is the mechanism of action of Levomefolate Calcium?
A: It works by bypassing the complex conversion process required by folic acid. It is readily absorbed into the bloodstream as active L-Methylfolate, which then:
Acts as a key cofactor in the synthesis of neurotransmitters like serotonin, dopamine, and norepinephrine.
Supports the healthy metabolism of homocysteine, helping to maintain it at normal levels.
Q: How much Levomefolate Calcium should I take per day?
A: Dosage depends on individual needs and purpose.
General Supplementation: A common dose ranges from 400 mcg to 800 mcg of L-Methylfolate.
Therapeutic Use: For specific needs like supporting mood or managing homocysteine, doses can range from 1 mg to 15 mg (1000-15,000 mcg) under medical supervision.
It is crucial to consult with a healthcare professional to determine the correct dosage for your specific health status.
1kg/aluminium foil bag, with two plastic bags inside.
Gross Weight: 1.5kg Size: 18cmxH27cm
25kg/fiber drum, with two plastic bags inside.
Gross Weight: 28kg Size: 42cmxH52cm Volume: 0.0625mg/Drum.
DHL / FEDEX / EMS / E-PACKET / BY AIR / BY SEA
1. ≤50kg, Express delivery(DHL /FEDEX) recommended, usually called as DDU service;
2. ≤500kg, Air shipping recommended, usually called as CIF service;
3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;
4. For high value products, please select air shipping and express delivery for safe.
We will contact you within 1 working day, please pay attention to the email with the suffix “forrest@oriherb.com”.
