| Product Name |
Guanfacine Hydrochloride (HCl) |
|---|---|
| CAS No. | 29110-48-3 |
| MF | C9H9Cl2N3O · HCl |
| MW | 282.56 g/mol |
| Specification | ≥99% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Packing | 1kg/bag; 25kg/drum (customized available) |
| Applications |
ADHD treatment research, antihypertensive drug formulations, CNS modulation studies |
Guanfacine HCl is an α2A adrenergic receptor agonist primarily used in attention deficit hyperactivity disorder (ADHD) management and hypertension therapy. Unlike stimulants, it has a non-addictive mechanism, making it suitable for long-term research in pediatric and adult populations.
Its pharmacological profile supports executive function, impulse control, and blood pressure regulation by reducing sympathetic nerve activity.
🧠 ADHD Research Applications – Improves attention, working memory, and reduces hyperactivity
❤️ Cardiovascular Regulation – Lowers blood pressure via sympathetic suppression
🛡️ Non-Stimulant Mechanism – Minimal abuse potential compared to amphetamine-based therapies
⚖️ Extended Release Potential – Stable plasma levels for long-acting effects
🔬 Broad R&D Uses – Psychiatric, neurological, and cardiovascular research
≥99% purity verified by HPLC
GMP-grade production ensuring safety & reproducibility
Pharmaceutical research-grade quality
Low impurity profile, compliant with USP standards
Bulk supply & OEM service available
| Specification | Qualified Testing Result | Actual Testing Result | Test Method |
|---|---|---|---|
| Part 1. Physical & Chemical Analysis | |||
| Appearance | White to off-white crystalline powder | Complied | Visual |
| Assay (HPLC) | ≥99.0% | 99.3% | HPLC |
| Melting Point | 214–220°C | 217.2°C | USP |
| Loss on Drying | ≤0.5% | 0.12% | USP <731> |
| Residue on Ignition | ≤0.1% | 0.04% | USP <281> |
| Part 2. Heavy Metal Analysis & Control | |||
| Total Heavy Metals | ≤10 ppm | Complied | AAS |
| Lead (Pb) | ≤3 ppm | <1 ppm | ICP-MS |
| Arsenic (As) | ≤1 ppm | <0.1 ppm | ICP-MS |
| Cadmium (Cd) | ≤1 ppm | <0.05 ppm | ICP-MS |
| Mercury (Hg) | ≤0.1 ppm | <0.01 ppm | ICP-MS |
| Part 3. Microbiological Analysis & Control | |||
| Total Plate Count (cfu/g) | ≤1,000 | <100 | USP <61> |
| Yeast & Mold (cfu/g) | ≤100 | <10 | USP <61> |
| E. coli | Negative | Negative | USP <62> |
| Salmonella (per 25 g) | Negative | Negative | USP <62> |
ADHD Research: Non-stimulant pharmacotherapy exploration
Hypertension Research: Blood pressure & cardiovascular regulation studies
Neuropharmacology: Role of α2A adrenergic modulation in cognition and mood
1kg/aluminium foil bag, with two plastic bags inside.
Gross Weight: 1.5kg Size: 18cmxH27cm
25kg/fiber drum, with two plastic bags inside.
Gross Weight: 28kg Size: 42cmxH52cm Volume: 0.0625mg/Drum.
DHL / FEDEX / EMS / E-PACKET / BY AIR / BY SEA
1. ≤50kg, Express delivery(DHL /FEDEX) recommended, usually called as DDU service;
2. ≤500kg, Air shipping recommended, usually called as CIF service;
3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;
4. For high value products, please select air shipping and express delivery for safe.
We will contact you within 1 working day, please pay attention to the email with the suffix “forrest@oriherb.com”.
