This article will be structured in a FAQ style, making it easy for buyers, pharmacists, and researchers to find quick answers. It will also naturally embed internal links back to the Pillar and other cluster pages.
Introduction
Sildenafil Citrate is one of the world’s best-known PDE5 inhibitors, used in treatments ranging from erectile dysfunction (ED) to pulmonary arterial hypertension (PAH). While most people recognize it in tablet form (Viagra®, Revatio®), the raw material actually comes as a white crystalline powder.
This FAQ article answers the most common questions about using sildenafil citrate powder in pharmaceutical compounding, storage, and sourcing.
👉 For a comprehensive overview of applications and procurement, see the Complete Buyer’s Guide to Sildenafil Citrate Powder.
FAQ 1: Can you take sildenafil citrate directly as powder?
No. Sildenafil powder is an API (Active Pharmaceutical Ingredient) and is not intended for direct human consumption. It must first be processed into finished dosage forms—such as tablets, capsules, or suspensions—under GMP (Good Manufacturing Practice) standards.
- Reason: Direct use poses risks of incorrect dosing, contamination, and regulatory violations.
- Correct use: APIs should be purchased by licensed companies for pharmaceutical or research use, not end consumers.
📌 If you need details on preparing suspensions, read How to Use Sildenafil Citrate Powder.
FAQ 2: What does sildenafil citrate powder look like?
It appears as a white to off-white crystalline powder.
- Solubility: Slightly soluble in water, more soluble in ethanol and DMSO.
- Taste: Bitter, chemical taste (not suitable for direct oral use).
- Form: Supplied in sealed aluminum foil bags (1–5 kg) or 25 kg fiber drums.
👉 For stability details, check How Long Does Sildenafil Powder Last? Storage & Shelf Life.
FAQ 3: What are the uses of sildenafil citrate powder?
Sildenafil citrate powder is primarily used to manufacture:
- Tablets & Capsules (25 mg, 50 mg, 100 mg for ED)
- Oral Suspensions (1–2 mg/mL for PAH)
- Chewable tablets and jellies in nutraceutical markets
- Research compounds in cardiovascular studies
👉 For wholesale sourcing options, see Sildenafil Citrate Powder Bulk Export Supply.
FAQ 4: How should sildenafil powder be measured?
- Use calibrated analytical balances for weighing.
- Dilute into stock solutions for precise dosing in research.
- Never rely on household or uncalibrated scales.
⚠️ Mis-measurement can lead to dangerous overdoses or sub-therapeutic dosing.
FAQ 5: How long does sildenafil powder last?
When stored properly:
- Temperature: 2–8°C
- Moisture: ≤60% relative humidity
- Shelf life: 24–36 months
Improper storage (heat, humidity, sunlight) causes degradation and discoloration.
👉 Full guidance available in Sildenafil Powder Stability & Storage.
FAQ 6: How much does sildenafil citrate powder cost?
Prices depend on origin, purity, and order volume:
- China (≥25 kg bulk): $400–$500/kg
- India (DMF/CEP-certified): $500–$650/kg
- US/EU distributors: $800–$1200/kg
For small trial batches (<5 kg), expect higher per-kilo rates.
📌 See Sildenafil Citrate Powder Price 2025: Factors & Regions for detailed breakdown.
FAQ 7: What documents should accompany sildenafil citrate powder?
A legitimate supplier will provide:
- Certificate of Analysis (COA)
- Material Safety Data Sheet (MSDS)
- GMP certificate
- DMF (for US) or CEP (for EU) filings
👉 Reference: Sildenafil Citrate Powder MSDS & Safety Guidelines.
FAQ 8: Who can buy sildenafil citrate powder online?
- Pharmaceutical companies (generic drug production)
- Nutraceutical OEM factories (formulations & supplements)
- Research labs (non-human experimental use)
- Distributors (bulk re-sellers)
It is not legally available for individual consumer purchase without proper licenses.
👉 To explore sourcing, visit Buy Sildenafil Citrate Powder Online.
FAQ 9: What are the risks of buying sildenafil citrate powder?
- Counterfeit products — substandard purity or contaminated batches.
- Lack of documentation — absence of COA, MSDS, DMF.
- Customs seizures — if regulatory paperwork is incomplete.
Buyers should always verify suppliers through DMF databases, request third-party testing, and avoid unrealistic low prices (<$300/kg).
👉 See vetted options in Top Sildenafil Citrate Powder Suppliers in China & India.
Conclusion
Sildenafil citrate powder is an essential API for multiple pharmaceutical and research applications. While it cannot be taken directly in powder form, it is the foundation for tablets, suspensions, and innovative dosage forms.
Key points for buyers:
- Never use powder directly; always process under GMP standards.
- Ensure stability with proper storage (2–8°C, sealed packaging).
- Verify all documents (COA, MSDS, GMP, DMF/CEP) before procurement.
- Buy only from GMP-certified suppliers in China or India.
By following these guidelines, B2B buyers can safely and effectively source sildenafil citrate powder, avoiding risks while ensuring regulatory compliance.