| Product Name |
Vardenafil Powder |
|---|---|
| CAS No. | 224785-90-4 |
| MF | C23H32N6O4S |
| MW | 488.6 g/mol |
| Specification | ≥99% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Packing | 1kg/bag; 25kg/drum (customized available) |
| Applications |
Erectile dysfunction (ED) treatment, pulmonary arterial hypertension |
Vardenafil is a highly selective phosphodiesterase type 5 (PDE5) inhibitor, widely recognized in vascular biology and nitric oxide signaling research. By inhibiting PDE5, Vardenafil increases cyclic GMP (cGMP) levels, supporting smooth muscle relaxation and vascular studies.
Compared with other PDE5 inhibitors such as Sildenafil, Vardenafil demonstrates higher potency, faster onset, and reduced PDE6-related effects, making it a valuable compound for formulation development and pharmacological research.
As a high-purity API (≥99%), Vardenafil is primarily supplied for laboratory use, formulation development, and pharmaceutical manufacturing.
⚡ Fast-acting Profile – Faster onset observed in pharmacological studies compared to other PDE5 inhibitors
🧬 High PDE5 Selectivity – Reduced interaction with PDE6, useful in comparative research studies
📊 Research Value – Supports investigation into nitric oxide–mediated vasodilation and vascular smooth muscle response
💊 Pharmaceutical-grade Purity – ≥99%, COA/MSDS available, suitable for R&D and formulation projects
≥99% purity verified by HPLC
GMP-certified manufacturing facilities
Complete COA, MSDS, and third-party test reports available
Stable bulk supply and flexible MOQ options
OEM/ODM service available for international markets
| Specification | Qualified Testing Result | Actual Testing Result | Test Method |
|---|---|---|---|
| Part 1. Physical & Chemical Analysis | |||
| Appearance | White crystalline powder | Complied | Visual |
| Assay (HPLC) | ≥99.0% | 99.4% | HPLC |
| Identification | Positive | Complied | IR, HPLC |
| Melting Point | 254–256 °C | 255.3 °C | USP |
| Loss on Drying | ≤0.5% | 0.11% | USP <731> |
| Residue on Ignition | ≤0.1% | 0.04% | USP <281> |
| Part 2. Heavy Metal Analysis & Control | |||
| Total Heavy Metals | ≤10 ppm | Complied | AAS |
| Lead (Pb) | ≤3 ppm | <1 ppm | ICP-MS |
| Arsenic (As) | ≤1 ppm | <0.1 ppm | ICP-MS |
| Cadmium (Cd) | ≤1 ppm | <0.05 ppm | ICP-MS |
| Mercury (Hg) | ≤0.1 ppm | <0.01 ppm | ICP-MS |
| Part 3. Microbiological Analysis & Control | |||
| Total Plate Count (cfu/g) | ≤1,000 | <100 | USP <61> |
| Yeast & Mold (cfu/g) | ≤100 | <10 | USP <61> |
| E. coli | Negative | Negative | USP <62> |
| Salmonella (per 25 g) | Negative | Negative | USP <62> |
Pharmaceutical Industry – API for formulation development in PDE5 inhibitor drug research
Research & Development – PDE5 inhibition mechanism studies, nitric oxide signaling, and vascular biology
Clinical Investigation – Raw material for clinical trials exploring new PDE5 inhibitor applications
Combination Studies – Evaluated in research settings for potential synergistic effects with other agents
1kg/aluminium foil bag, with two plastic bags inside.
Gross Weight: 1.5kg Size: 18cmxH27cm
25kg/fiber drum, with two plastic bags inside.
Gross Weight: 28kg Size: 42cmxH52cm Volume: 0.0625mg/Drum.
DHL / FEDEX / EMS / E-PACKET / BY AIR / BY SEA
1. ≤50kg, Express delivery(DHL /FEDEX) recommended, usually called as DDU service;
2. ≤500kg, Air shipping recommended, usually called as CIF service;
3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;
4. For high value products, please select air shipping and express delivery for safe.
We will contact you within 1 working day, please pay attention to the email with the suffix “forrest@oriherb.com”.
