| Product Name |
Agomelatine Powder |
|---|---|
| CAS No. | 138112-76-2 |
| MF | C15H17NO2 |
| MW | 243.30 g/mol |
| Specification | ≥99% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Packing | 1kg/bag; 25kg/drum (customized available) |
| Applications |
Antidepressant, sleep regulator, circadian rhythm stabilizer |
Agomelatine Powder is a novel melatonergic antidepressant, functioning as an agonist of melatonin receptors (MT1 & MT2) and an antagonist of serotonin 5-HT2C receptors. Unlike traditional antidepressants, Agomelatine restores circadian rhythm balance and improves sleep quality while relieving depressive symptoms.
It is widely recognized for its dual benefits: treating major depressive disorder (MDD) and supporting healthy sleep cycles, making it highly valuable in psychiatric and wellness applications.
🌙 Sleep-Wake Regulation – Improves circadian rhythm and enhances sleep quality
🧠 Antidepressant Effect – Effective in major depressive disorder with fewer side effects
⚡ Cognitive Clarity – Reduces fatigue and enhances daytime alertness
🛡️ Neuroprotection – Supports brain resilience against stress and oxidative damage
🌱 Better Tolerability – Minimal sexual dysfunction and weight gain compared to SSRIs
High-purity API (≥99%) confirmed by HPLC
Pharmaceutical-grade quality with GMP & ISO certification
Stable production and global export experience
Rigorous control of heavy metals and microbial limits
Customized packaging to meet customer needs
| Specification | Qualified Testing Result | Actual Testing Result | Test Method |
|---|---|---|---|
| Part 1. Physical & Chemical Analysis | |||
| Appearance | White to off-white crystalline powder | Complied | Visual |
| Odor | Characteristic | Complied | Organoleptic |
| Assay (HPLC) | ≥99.0% | 99.5% | HPLC |
| Melting Point | 107–110°C | 108.3°C | USP |
| Loss on Drying | ≤0.5% | 0.11% | USP <731> |
| Residue on Ignition | ≤0.1% | 0.04% | USP <281> |
| Part 2. Heavy Metal Analysis & Control | |||
| Total Heavy Metals | ≤10 ppm | Complied | AAS |
| Lead (Pb) | ≤3 ppm | <1 ppm | ICP-MS |
| Arsenic (As) | ≤1 ppm | <0.1 ppm | ICP-MS |
| Cadmium (Cd) | ≤1 ppm | <0.05 ppm | ICP-MS |
| Mercury (Hg) | ≤0.1 ppm | <0.01 ppm | ICP-MS |
| Part 3. Microbiological Analysis & Control | |||
| Total Plate Count (cfu/g) | ≤1,000 | <100 | USP <61> |
| Yeast & Mold (cfu/g) | ≤100 | <10 | USP <61> |
| E. coli | Negative | Negative | USP <62> |
| Salmonella (per 25 g) | Negative | Negative | USP <62> |
Pharmaceuticals: Treatment of major depressive disorder (MDD)
Nutraceuticals: Sleep support and circadian rhythm modulation formulas
Neuroprotective Research: Studies on depression, anxiety, and brain health
1kg/aluminium foil bag, with two plastic bags inside.
Gross Weight: 1.5kg Size: 18cmxH27cm
25kg/fiber drum, with two plastic bags inside.
Gross Weight: 28kg Size: 42cmxH52cm Volume: 0.0625mg/Drum.
DHL / FEDEX / EMS / E-PACKET / BY AIR / BY SEA
1. ≤50kg, Express delivery(DHL /FEDEX) recommended, usually called as DDU service;
2. ≤500kg, Air shipping recommended, usually called as CIF service;
3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;
4. For high value products, please select air shipping and express delivery for safe.
We will contact you within 1 working day, please pay attention to the email with the suffix “forrest@oriherb.com”.
