| Product Name |
Calcium Orotate |
|---|---|
| Synonym | Calcium salt of orotic acid |
| CAS No. | 4075-81-4 |
| MF | C10H6CaN2O8 |
| MW | 334.24 g/mol |
| Specification | ≥98% (HPLC) |
| Appearance | White crystalline powder |
| Packing | 1kg/bag; 25kg/drum (customized available) |
| Applications |
Nutritional supplements, bone health, cardiovascular support |
Calcium Orotate is a bioavailable form of calcium, bound to orotic acid, a natural compound involved in nucleic acid metabolism. It is known for its enhanced cellular transport, allowing calcium to penetrate cell membranes more efficiently compared to conventional calcium salts like carbonate or citrate.
This property makes it especially effective in bone health, cardiovascular function, and healthy aging formulations. It is widely used in nutraceuticals, dietary supplements, and clinical research targeting osteoporosis and calcium deficiency.
🦴 Bone Density Support – Improves calcium utilization in skeletal tissue
❤️ Cardiovascular Health – Supports healthy muscle contraction and vascular function
👵 Healthy Aging – Helps prevent age-related calcium loss
⚡ Enhanced Absorption – Superior bioavailability compared to common calcium salts
🛡 Nucleotide Synergy – Orotic acid supports cellular metabolism
≥98% purity verified by HPLC
Produced under GMP, ISO, and HACCP standards
High absorption efficiency compared to calcium carbonate/citrate
Low heavy metals, microbiologically safe
Customizable particle size & bulk packaging
| Specification | Qualified Testing Result | Actual Testing Result | Test Method |
|---|---|---|---|
| Part 1. Physical & Chemical Analysis | |||
| Appearance | White crystalline powder | Complied | Visual |
| Odor | Characteristic | Complied | Organoleptic |
| Assay (HPLC) | ≥98.0% | 98.9% | HPLC |
| Calcium Content | ≥16.0% | 16.4% | ICP-OES |
| Loss on Drying | ≤1.0% | 0.12% | USP <731> |
| Residue on Ignition | ≤0.5% | 0.04% | USP <281> |
| Part 2. Heavy Metal Analysis & Control | |||
| Total Heavy Metals | ≤10 ppm | Complied | AAS |
| Lead (Pb) | ≤3 ppm | <1 ppm | ICP-MS |
| Arsenic (As) | ≤1 ppm | <0.1 ppm | ICP-MS |
| Cadmium (Cd) | ≤1 ppm | <0.05 ppm | ICP-MS |
| Mercury (Hg) | ≤0.1 ppm | <0.01 ppm | ICP-MS |
| Part 3. Microbiological Analysis & Control | |||
| Total Plate Count (cfu/g) | ≤1,000 | <100 | USP <61> |
| Yeast & Mold (cfu/g) | ≤100 | <10 | USP <61> |
| E. coli | Negative | Negative | USP <62> |
| Salmonella (per 25 g) | Negative | Negative | USP <62> |
Nutraceuticals: Tablets, capsules, bone/joint health blends
Functional Foods: Fortified powders, beverages
Clinical Nutrition: Used in osteoporosis and deficiency studies
Sports & Anti-Aging Supplements: Combines with Vitamin D3, K2, Magnesium
Q: Is calcium orotate the best form of calcium?
A: For targeted bone and heart health, calcium orotate is considered superior by some experts due to its unique orotic acid component, which may enhance mineral transport directly into bone matrix and mitochondria. However, “best” depends on your needs:
Calcium Citrate: Most recommended general form (good absorption with/without food)
Calcium Orotate: Premium choice for deep tissue penetration and cellular efficiency
Q: What is calcium orotate made from?
A: It’s a compound formed by combining calcium with orotic acid (a naturally occurring compound in the body and in some root vegetables). The resulting molecule is a single compound rather than a mixture.
Q: How is calcium citrate different from calcium orotate?
A:
| Feature | Calcium Citrate | Calcium Orotate |
|---|---|---|
| Absorption | Good bioavailability, less dependent on stomach acid | Potentially superior cellular absorption |
| Primary Use | General bone health, osteoporosis prevention | Deep bone support, cardiovascular health |
| Mechanism | Provides calcium + citric acid | Calcium + orotic acid (enhances mineral transport) |
| Research | Extensive clinical evidence | Growing evidence for specialized applications |
Q: How much calcium orotate should I take?
A: Typical dosing is 500-1,000 mg daily, providing 50-100 mg of elemental calcium. Since it’s highly bioavailable, lower doses may be sufficient compared to other forms. Always check the elemental calcium content on your product label.
Q: Is calcium orotate better than calcium?
A: Calcium orotate IS calcium – just in a specific, highly bioavailable form. The question should be: “Is calcium orotate better than other forms of calcium?” For general supplementation, calcium citrate remains the gold standard, but for advanced cellular support and bone density applications, calcium orotate offers distinct advantages due to its enhanced transport mechanisms.
1kg/aluminium foil bag, with two plastic bags inside.
Gross Weight: 1.5kg Size: 18cmxH27cm
25kg/fiber drum, with two plastic bags inside.
Gross Weight: 28kg Size: 42cmxH52cm Volume: 0.0625mg/Drum.
DHL / FEDEX / EMS / E-PACKET / BY AIR / BY SEA
1. ≤50kg, Express delivery(DHL /FEDEX) recommended, usually called as DDU service;
2. ≤500kg, Air shipping recommended, usually called as CIF service;
3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;
4. For high value products, please select air shipping and express delivery for safe.
We will contact you within 1 working day, please pay attention to the email with the suffix “forrest@oriherb.com”.
