A comprehensive analysis of the Oxandrolone Anavar


Anavar (Oxandrolone) was originally developed and named “Oxandrin” by physician Raphael Pappo, one of the researchers at Searle Laboratories. He developed Anavar around 1964, and the drug was used to treat a variety of diseases, including muscular dystrophy. At that time, anabolic steroids were virtually unheard of in the marketplace, and he was one of the first pioneers in the use of oral steroids for bodybuilding purposes. Later, Pfizer Pharmaceuticals acquired Searle Laboratories, and Anavar’s production was temporarily interrupted.

And when the AIDS epidemic began in the early 1980s, Anavar and Androl (Oxymetholone), Rehab Long became the prescription of choice when addressing muscle atrophy. Why is this? Because Anavar helped people gain lean body mass (muscle) with little to no water retention, it also increased the user’s strength, which was a great help to the patient.

There was a magazine, “Muscle Media 2000” (the first national magazine to talk openly about steroids), which gave Anavar a very high rating for its effectiveness (and was also rated as having the least side effects). At this point, Anavar began to make a splash with bodybuilders, other competitive athletes, and fitness enthusiasts. The magazine noted that Anavar’s very low toxicity and the incredible results it gave users led directly to this “fringe” drug suddenly becoming one of the most popular steroids.

1. Chemical Structure

The molecular structure of Anavar is 5-alpha-androstane-2-oxa-17alpha-methyl-17beta-ol-3-one, a molecular structure derived from dihydrotestosterone synthesized by Raphael Pappo in the development of the formulation. The key difference is the substitution of an oxygen atom for the methylation and the two carbons at the 17 position. Anavar was originally intended to be designed as a milder form of Dianabol – more anabolic and less androgenic force, thus eliminating many side effects. This was achieved by replacing other elements normally found in dihydrotestosterone with oxygen. Through this process, Pappo has succeeded in creating a steroid that has the lowest rate of androgen production of any of the anabolic steroids.

2. Introduction

Anavar is a very interesting drug. It seems to defy the definition and limitations of oral steroids, and you may have learned information about its excellent effects and low side effects. Oddly enough, it is so safe that unlike other steroids originally used for malnutrition and anemia, Anavar was originally used as a prescription drug for burn patients. In a randomized, double-blind study, patients with a total body surface area burn of 40% were targeted to receive standard burn care, the difference being that one group was added to Anavar and the other was not. Anavar was used to help restore patients after surgery for weight loss, severe trauma, or chronic infection. The results were that the Anavar-treated group healed faster, retained more muscle, had less catabolism, and had shorter hospital stays. No wonder bodybuilders are interested in it!

Some people may think Anavar seems overrated; this is because, with Anavar, you don’t gain as much weight due to water retention as you do with Dianabol or Anadrol (Oxymetholone) or Test (testosterone). But no one can deny the quality of muscle and longevity gained through the use of Anavar. On top of that, Anavar’s often-discussed effectiveness in fat loss.

Many people claim that Anavar is helpful in burning fat. In fact, any steroid can increase muscle and burn fat. However, people usually tend to use Anavar. People will look leaner, and the muscle lines will seem more defined. The reason for this is that Anavar does not retain water. In addition, studies have shown that Anavar can significantly reduce visceral fat in the abdominal region as long as the training intensity is moderate or higher. And the subjects maintained it even after they stopped using Anavar.

In short, Anavar is an “advanced” steroid. It can give you high-quality muscle and is relatively safe if used properly. It can be used to start a Cycle, and it also does a good job as a “Cycle finisher” that you can use before a race or photo shoot to get your muscles more defined. But remember, although Anavar has minimal side effects, you still need to do an effective post-Cycle treatment (PCT) to ensure safety along the way.

3. Applications, Dosage, and Uses

Typically, Anavar is only taken orally; however, some people crush the tablets and mix them with liquid, partly to increase purity, but in fact, it degrades in the liquid instead, so this is not recommended. Since grapefruit juice can improve the efficacy of many medications, there may be some benefits to taking it with grapefruit juice. Grapefruit juice can cause problems with P-glycoproteins and organic anion-transporting polypeptides (OATPs), thereby improving the bioavailability of many drugs. But ironically, this is why grapefruit juice is not recommended to be taken with any drug or medication. But in any case, in our case, there is a reason to use grapefruit juice to help us have better results.

The standard effective dose of Anavar is 25-50mg/d for men and 5-20mg/d for women.

For male users, I recommend splitting the dose into the morning (50% dose) and pre-workout (50% dose). For females, a pre-workout 50% dose and a post-workout 50% dose are best.

4. Cycle Dosing

As with most oral steroids, Anavar should be paired with at least one injection. This pairing of Anavar and Test testosterone works very, very well. Of course, at the end of the Cycle, a full PCT is recommended for recovery and consolidating the results.

Another highly effective Cycle combination is using Anavar with another oral steroid and/or Sarms. Combining Anavar, Winstrol, and Cardarine (GW-501516) will combine to make a Cycle with extremely high fat loss capacity and few side effects. It is ideal for those who do not want to add injectables to their Cycle: Anavar+Winstrol+GW1516.

5. Half-life period

Anavar has a half-life of only 10 hours. Therefore multiple dosing is recommended. 25mg in the morning and 25mg before training is best.

6. Duration of the assay

Although there is some debate about the duration of the Anavar assay, it is about three weeks, according to my research. But to be on the safe side, I recommend four weeks.

7. Side effects One of the reasons

Anavar has such a reputation for safety is that Anavar is not hepatotoxic compared to other oral steroids, and it is available to people with liver damage and alcoholic hepatitis! Studies have shown that over 6 weeks, the use of 20 mg of Anavar daily had a negligible effect on the increase in hepatic transaminases; Anavar decreased hepatic acute phase protein concentrations and increased constitutive hepatic protein concentrations. This indicates an improvement in the liver’s in vivo balance and protein production. There was no significant difference in liver size and weight between the control and Anavar groups, indicating that Anavar does not cause liver enlargement (hepatomegaly). In short, Anavar does not cause damage to the liver in the smaller dose range.

In addition, Anavar has little to no effect on blood pressure, unlike many other anabolic androgens (AAS). However, you can’t assume that this drug is completely safe yet; Anavar is still a 17-alpha alkylated drug, which simply means that it can affect the liver’s ability to break down the active ingredient because it can also cause liver damage if used at too high a dose or for too long. The definition of too long is 12-14 weeks, and the definition of high doses is much more difficult (and subjective), but generally, Anavar is not recommended at doses above 150 mg/d.

One thing to remember in particular is that Anavar’s “mild nature” is based primarily on early studies when doses ranged from 2-15 mg/d. Between mg. The original Anavar produced by Searle Laboratories was 2.5mg/tablet, two daily tablets for therapeutic use. At these doses, the side effects were negligible. But in the bodybuilding field, would anyone use just 5mg per day? -Most people take a dose of around 50mg.

Another possible side effect is its effect on cholesterol. Anavar at 50mg daily will raise LDL after only two weeks – that is the standard dose. Remember, we do not recommend using Anavar alone; it must always be stacked with another drug for the best results. If you can use it with testosterone, then the effect on LDL is much less. Anavar does not cause aromatization. Therefore, it does not convert to estrogen.

8. Female users

Anavar is a favorite among women because of its low androgen ratio. Women can gain superhuman muscles by taking it without worrying about excessive hair, voice heaviness, or clitoral enlargement caused by most other steroids. Another attractive aspect of Anavar for women is that (somewhat empirically) it helps to reduce body fat, especially in the abdominal area.

9. Conclusion

What makes Anavar so popular? Because it works so incredibly well!!! Anavar produces the ultimate look that most people want. Your body fat is low, your muscles are hard, your blood vessels are visible, there is no puffiness, your skin is tight, and the results show up fast! You can see results within a few days of taking it. This brings up another point: Whenever someone says that steroids take months to “get started,” they may not know what they are doing in terms of training. Oral steroids will work immediately (within 1-2 weeks). Of course, you can’t change your body overnight. However, if you are in good shape and you are training hard, eating right, supplementing properly, and starting Anavar, then by the end of the week, you will notice a change in your muscles; it is so powerful.

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